The president urged states to follow suit and directed the Feds to review how marijuana is classified in federal drug laws.
Late returns appear to have won the vote making Denver the first city to decriminalize psilocybin in a historic municipal vote.
Denver may become the first city in the nation to allow possession of personal quantities of psilocybin if a controversial ballot initiative passes on Tuesday.
Spravato (aka Esketamine) will be administered by nasal spray and is the first fast-acting treatment of its kind.
Better known as "club drug" Special K, ketamine has shown remarkable potential in treating depressed or suicidal patients.